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The oxycodone in OXYCONTIN may increase the frequency of seizures in individuals with seizure disorders and will enhance the chance of seizures transpiring in other clinical configurations associated with seizures.
If opioid use is needed for a protracted interval in pregnant Females, advise the patient of the risk of neonatal opioid withdrawal syndrome and make sure proper treatment is going to be obtainable.
When controlling patients getting opioid analgesics, specifically individuals who have been taken care of for an extended time period and/or with significant doses for Serious suffering, make sure that a multimodal method of pain management, including mental wellbeing assist (if necessary), is in position ahead of initiating an opioid analgesic taper.
Patients may also nutritional supplement their treatment with extra soreness relievers. These may be signals the individual is building tolerance. The risks of developing tolerance must be explained into the patient.
This is especially critical for elderly individuals, who could be more delicate to the consequences of suffering medicines. If far too much of the medication is taken for a long period, it may come to be habit-forming (creating psychological or Actual physical dependence).
Oxycodone is used to relieve soreness critical sufficient to have to have opioid remedy and when other pain medicines did not do the job well enough or cannot be tolerated.
Because the use of OXYCONTIN exposes individuals along with other consumers for the threats of opioid dependancy, abuse, and misuse, which may lead to overdose and Loss of life, assess Every affected individual's hazard just before prescribing and reassess all clients regularly for the event of those behaviors and circumstances [see Warnings and Safety measures (five.1)].
Drug interactions may perhaps improve how your medications function or enhance your hazard for really serious Unwanted side effects. This document isn't going to comprise all probable get more info drug interactions.
If a CYP3A4 inhibitor is discontinued, consider growing the OXYCONTIN dosage until steady drug consequences are reached. Evaluate for signs of opioid withdrawal.
Notify your healthcare supplier about all the medicines you are taking, including prescription and non-prescription medicines, nutritional vitamins, and herbal supplements. Sometimes the doses of medicines you get with OxyContin may perhaps need to be transformed if made use of with each other.
In case you have questions about getting a reduced-Charge different to oxycodone, talk with your medical professional or pharmacist.
Breastfeeding Administration to nursing Ladies just isn't encouraged as oxycodone may very well be secreted in breast milk and could cause respiratory despair from the toddler.
If opioid cure is taken into account appropriate for the individual, then the key purpose of treatment is to not minimise the dose of opioid but somewhat to realize a dose which provides ample soreness reduction with at least Uncomfortable side effects. See portion four.2 For extra information on therapy plans and discontinuation. Tolerance, Dependence and Opioid Use Dysfunction Tolerance and Actual physical and/or psychological dependence might establish upon repeated administration of opioids like oxycodone. Recurring usage of OxyContin tablets may perhaps cause Opioid Use Condition (OUD). A better dose and more time period of opioid cure can enhance the chance of building OUD. Abuse or intentional misuse of OxyContin tablets may cause overdose and/or Demise.
• Right before getting OxyContin, tell your health care provider if you or even a member of the family are hooked on or abused other medicines, Avenue medications, or Liquor, or When you have a heritage of mental disease.